Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 190
interventional 133
Observational 44
Registry 13

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Procedure 30
Device 24
Drug 22
Other 16
Device|Procedure 7
Drug|placebo 5
Behavioral 3
Behavioral|Other 3
Diagnostic Test 3
Drug|Procedure 3
Other|Procedure 3
Biological|Procedure 2
Device|Other 2
Drug|Other 2
Behavioral|Device|placebo 1
Biological 1
Biological|Device 1
Combination Product 1
Device|Drug 1
Device|placebo 1
Drug|Other|Procedure 1
placebo|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 54
Korea, Republic of 16
Canada 9
NA 9
China 7
Sweden 4
Turkey 4
Netherlands 3
Switzerland 3
Czechia 2
Denmark 2
Israel 2
Taiwan 2
Australia 1
Australia|Belgium|France|Germany|Iceland|Italy|Poland|Singapore|Sweden|United Kingdom 1
Belgium 1
Belgium|Germany|United Kingdom 1
France 1
Germany 1
Germany|Hungary|Ireland|Spain|United Kingdom 1
Germany|Netherlands|Switzerland 1
Greece 1
Hong Kong 1
Norway 1
Spain 1
Thailand 1
United Kingdom 1
United States|Canada 1
United States|Puerto Rico 1

Sites per Study

Site_count Study_Count
1 90
2 9
3 4
4 3
5 2
7 1
8 4
10 1
11 1
12 2
13 4
14 1
15 2
16 1
18 1
19 2
27 1
28 1
29 2
32 1

Phase

Phase Study_Count
N/A 91
Phase 4 26
Phase 3 6
Phase 1/Phase 2 3
Phase 2 3
Early Phase 1 2
Phase 2/Phase 3 2

Number of Arms

Number_of_Arms Count_of_Studies
1 24
2 89
3 11
4 3
6 2
NA 4

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 49.00 8.0000 6.00000 24 22.00 66.0000 17.0000
1st Qu. 96.75 55.5000 9.00000 24 27.75 112.5000 40.5000
Median 144.50 104.0000 12.00000 24 33.50 164.0000 68.5000
Mean 144.50 153.1319 34.66667 36 33.50 207.6667 106.5385
3rd Qu. 192.25 196.5000 49.00000 42 39.25 271.0000 149.0000
Max. 240.00 1000.0000 86.00000 60 45.00 450.0000 400.0000

Trial Group Type

group_type Group_Count
Experimental 101
Active Comparator 98
Other 24
Placebo Comparator 17
No Intervention 16
NA 4
Sham Comparator 3

Intervention Model

intervention_model Study_Count
Parallel Assignment 101
Single Group Assignment 28
Crossover Assignment 2
Factorial Assignment 1
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 113
Prevention 8
Diagnostic 4
Other 4
Health Services Research 3
Supportive Care 1

Observational Studies

Studies by Country

Country Study_Count
United States 14
Korea, Republic of 5
Switzerland 5
France 3
NA 3
Canada 2
Denmark 2
Netherlands 2
Norway 2
Turkey 2
China 1
Germany 1
Germany|Spain 1
Taiwan 1

Sites per Study

Site_count Study_Count
1 34
2 3
3 2
5 3
7 1
601 1

Enrollment Metrics

Measure Observational
Min 15.000
1st Qu 59.500
Median 110.000
Mean 2639.136
3rd Qu 255.000
Max 100000.000

Observation Model

observational_model Study_Count
Cohort 34
Case-Only 4
Other 4
Case-Control 2

Time Perspective

time_perspective Study_Count
Prospective 28
Retrospective 8
Other 5
Cross-Sectional 3

Registries

Studies by Country

Country Study_Count
United States 6
Denmark 2
Austria|France|Germany|Netherlands|Switzerland 1
Canada 1
Italy 1
Korea, Republic of 1
NA 1

Sites per Study

Site_count Study_Count
1 10
4 1
13 1
28 1

Enrollment Metrics

Measure Registries
Min 20.000
1st Qu 100.000
Median 450.000
Mean 2044.154
3rd Qu 1665.000
Max 10000.000

Registry Model

observational_model Study_Count
Cohort 9
Other 4

Time Perspective

time_perspective Study_Count
Prospective 13

Follow-up

target_duration Study_Count
2 Years 3
1 Year 2
60 Months 2
10 Years 1
12 Months 1
3 Months 1
5 Years 1
6 Months 1
8 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03480893 Cost-effectiveness of Small Size Interarcuair Decompression Versus Extended Decompression in Patients With Intermittent Neurogenic Claudication https://ClinicalTrials.gov/show/NCT03480893 Recruiting Erasmus Medical Center 2022-04-01
NCT03388983 Effectiveness of Prehabilitation for Patients Undergoing Lumbar Spinal Stenosis Surgery https://ClinicalTrials.gov/show/NCT03388983 Recruiting The Hong Kong Polytechnic University 2021-12-31
NCT03381677 Pedicle Osteotomy for Stenosis Trial https://ClinicalTrials.gov/show/NCT03381677 Recruiting Innovative Surgical Designs 2022-10-26
NCT03368638 Physical Therapy Treatments, Including Neural Mobilization and Hip/Back Stretches for People Between 50-89 With Lumbar Spinal Stenosis and Leg Pain Provoked by Walking https://ClinicalTrials.gov/show/NCT03368638 Active, not recruiting Texas Tech University Health Sciences Center 2019-10-22
NCT04166981 Instr. vs. Non-instr. Posterolateral Spinal Fusion in Patients With Spinal Stenosis and Degenerative Listhesis https://ClinicalTrials.gov/show/NCT04166981 Recruiting Spine Centre of Southern Denmark 2021-09-01
NCT03337178 Fitbit Pilot Study in Post-operative Lumbar Degenerative Spinal Stenosis Patients https://ClinicalTrials.gov/show/NCT03337178 Recruiting The London Spine Centre 2019-08-31
NCT03302520 Comparison of Bioactive Glass Ceramics Spacer and PEEK Cages in Posterior Lumbar Interbody Fusion: A Prospective, RCT https://ClinicalTrials.gov/show/NCT03302520 Active, not recruiting Seoul National University Hospital 2019-07-11
NCT03302507 Biportal Endoscopy Spine Surgery (BESS )Versus Unilateral Laminotomy Bilateral Decompression (ULBD ): RCT, Non-inferiority Trial https://ClinicalTrials.gov/show/NCT03302507 Completed Seoul National University Hospital 2019-06-30
NCT03167736 Dry Needling and Spinal Manipulation vs. Conventional PT for Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT03167736 Recruiting Alabama Physical Therapy & Acupuncture 2020-03-15
NCT03115983 LimiFlex Clinical Trial for the Treatment of Degenerative Spondylolisthesis With Spinal Stenosis https://ClinicalTrials.gov/show/NCT03115983 Recruiting Empirical Spine, Inc. 2020-12-31
NCT03105167 Cortical Bone Trajectory Screws vs. Traditional Pedicle Screws Fixation https://ClinicalTrials.gov/show/NCT03105167 Recruiting Second Affiliated Hospital of Wenzhou Medical University 2020-12-13
NCT03088306 Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients https://ClinicalTrials.gov/show/NCT03088306 Completed Johns Hopkins University 2018-05-31
NCT03047044 The Comparison of Postoperative Pain After Lumbar Fusion Surgery in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With ‘PAINSTOP’ Equipment https://ClinicalTrials.gov/show/NCT03047044 Completed Yonsei University 2019-01-30
NCT03012776 A Pivotal Study of the Premia Spine TOPSâ„¢ System https://ClinicalTrials.gov/show/NCT03012776 Recruiting Premia Spine 2020-09-30
NCT02939482 A Study Comparison of Clinical Outcome After Different Rate of Infusion in Caudal Epidural Steroid Injection https://ClinicalTrials.gov/show/NCT02939482 Completed Navamindradhiraj University 2018-08-02
NCT02902380 The Effect of Dexmedetomidine on Neuroendocrine Stress Hormone Release and Heart Rate Variability in Patients Undergoing Major Spinal Surgery https://ClinicalTrials.gov/show/NCT02902380 Completed Yonsei University 2017-07-01
NCT02895555 The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumentated Posterolateral Fusionin The IVANOS-study https://ClinicalTrials.gov/show/NCT02895555 Completed Sygehus Lillebaelt 2016-01-31
NCT02838615 Comparison of Transforaminal vs. Parasagittal Interlaminar Epidural Injection https://ClinicalTrials.gov/show/NCT02838615 Completed Keimyung University Dongsan Medical Center 2017-05-31
NCT02826889 Assessing the Diagnostic Accuracy of Corrected Flow Time (FTc) and Pleth Variability Index (PVI) as Predictors of Fluid Responsiveness in Patients in the Prone Position Using the Jackson Table https://ClinicalTrials.gov/show/NCT02826889 Completed Yonsei University 2017-07-27
NCT02700451 Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes https://ClinicalTrials.gov/show/NCT02700451 Active, not recruiting Hospital for Special Surgery, New York 2020-12-31
NCT02697435 Making Better Lives: Patient-Focused Care for Low Back Pain (LBP) https://ClinicalTrials.gov/show/NCT02697435 Completed VA Office of Research and Development 2018-05-31
NCT02625194 The Utility of Oxygen Insufflation During Flexible Fiberoptic Bronchoscope-guided Intubation https://ClinicalTrials.gov/show/NCT02625194 Completed Yonsei University 2017-09-04
NCT02592642 the Evaluation of Four Non-operative Treatments for Degenerative Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT02592642 Completed Mount Sinai Hospital, Canada 2017-02-15
NCT02558621 New Robotic Assistance System for Spinal Fusion Surgery https://ClinicalTrials.gov/show/NCT02558621 Completed KB Medical SA 2016-05-31
NCT02555280 Post-Approval ‘Real Conditions of Use’ Study https://ClinicalTrials.gov/show/NCT02555280 Recruiting Paradigm Spine 2024-09-30
NCT01106417 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion https://ClinicalTrials.gov/show/NCT01106417 Completed Mesoblast, Ltd. 2012-05-31
NCT02464553 EuroPainClinics® Study I (Prospective Trial) https://ClinicalTrials.gov/show/NCT02464553 Recruiting Europainclinics z.ú. 2021-05-31
NCT02459392 EuroPainClinics® Study II (Prospective Trial) https://ClinicalTrials.gov/show/NCT02459392 Recruiting Europainclinics z.ú. 2021-11-30
NCT02444351 Botulinum Toxin Type A Injection Into the Gastrocnemius Muscle for Treatment of Nocturnal Calf Cramps in Patients With Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT02444351 Completed Yonsei University 2016-06-30
NCT02348645 Decompression vs. Fusion for Stable Degenerative Spondylolisthesis https://ClinicalTrials.gov/show/NCT02348645 Recruiting University Health Network, Toronto 2022-06-30
NCT02341950 Clinical Trial of a Serious Game for Individuals With SCI/D https://ClinicalTrials.gov/show/NCT02341950 Completed University of Michigan 2017-09-01
NCT02300909 dHACM in Lumbar Decompression and Microdiscectomy Surgery https://ClinicalTrials.gov/show/NCT02300909 Completed MiMedx Group, Inc. 2018-06-30
NCT02271191 Effect of Nicardipine on Renal Function in Deliberate Hypotension https://ClinicalTrials.gov/show/NCT02271191 Completed Yonsei University 2013-01-31
NCT02260401 Long Term Outcomes of Lumbar Epidural Steroid Injections for Spinal Stenosis https://ClinicalTrials.gov/show/NCT02260401 Completed University of Washington 2015-07-31
NCT02258672 Preoperative Rehabilitation for Patients Undergoing Surgery for Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT02258672 Completed Université du Québec à Trois-Rivières 2020-03-01
NCT02254590 Irrigation Endoscopic Decompression https://ClinicalTrials.gov/show/NCT02254590 Completed Cairo University 2014-03-31
NCT02252185 A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery https://ClinicalTrials.gov/show/NCT02252185 Completed Johnson & Johnson Medical (Suzhou) Ltd. 2015-09-30
NCT02127008 The Impact of Epidural Fat Resection on Postoperative Outcomes in Posterior Surgery of Lumbar Spine https://ClinicalTrials.gov/show/NCT02127008 Completed Seoul National University Hospital 2014-05-31
NCT02121249 Clinical Trial of Minimally Invasive Robotic Spine Surgery https://ClinicalTrials.gov/show/NCT02121249 Completed Seoul National University Hospital 2014-04-30
NCT02093520 The MiDAS ENCORE Study https://ClinicalTrials.gov/show/NCT02093520 Completed Vertos Medical, Inc. 2016-05-31
NCT02090244 Does PTH 1-34 (Teriparatide) Enhance Spinal Fusion in Humans? https://ClinicalTrials.gov/show/NCT02090244 Completed University Hospital, Linkoeping 2018-05-31
NCT02079038 The STEPS - Totalisâ„¢ Trial https://ClinicalTrials.gov/show/NCT02079038 Completed VertiFlex, Incorporated 2017-01-31
NCT02063035 Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery https://ClinicalTrials.gov/show/NCT02063035 Completed Massachusetts General Hospital 2015-04-22
NCT01316211 Clinical Trial Comparing Decompression With and Without Coflexâ„¢ Interlaminar Technology Treating Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT01316211 Completed Paradigm Spine 2014-08-31
NCT01315145 MiDAS III (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study https://ClinicalTrials.gov/show/NCT01315145 Completed Vertos Medical, Inc. 2014-05-31
NCT01275547 The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam https://ClinicalTrials.gov/show/NCT01275547 Completed University Hospital, Basel, Switzerland 2011-06-30
NCT02023372 Efficacy Study of NuCel® in Patients Undergoing Fusion of the Lumbar Spine https://ClinicalTrials.gov/show/NCT02023372 Completed NuTech Medical, Inc 2019-08-16
NCT02039232 Safety and Efficacy of the CarboFix Pedicle Screw System https://ClinicalTrials.gov/show/NCT02039232 Completed CarboFix Orthopedics Ltd. 2017-08-31
NCT02007083 The NORDSTEN Studies/ The Spinal Stenosis Study https://ClinicalTrials.gov/show/NCT02007083 Active, not recruiting Haukeland University Hospital 2025-10-31
NCT01994512 Swedish Spinal Stenosis Study https://ClinicalTrials.gov/show/NCT01994512 Completed Uppsala University 2012-06-30
NCT01991912 Irrigation Endoscopic Decompressive Laminotomy https://ClinicalTrials.gov/show/NCT01991912 Completed Cairo University 2012-06-30
NCT01987622 Acupuncture for Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT01987622 Completed Korean Medicine Hospital of Pusan National University 2014-09-30
NCT01968993 Comparison of nanOss Bioactive With Autograft and Bone Marrow Aspirate to Autograft in the Posterolateral Spine https://ClinicalTrials.gov/show/NCT01968993 Completed Pioneer Surgical Technology, Inc. 2015-10-31
NCT01943435 Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis) https://ClinicalTrials.gov/show/NCT01943435 Completed University of Pittsburgh 2016-06-07
NCT01934868 Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg https://ClinicalTrials.gov/show/NCT01934868 Active, not recruiting Hadassah Medical Organization 2021-04-30
NCT01921530 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis https://ClinicalTrials.gov/show/NCT01921530 Recruiting The London Spine Centre 2018-12-31
NCT01888536 A Study to Evaluate Efficacy of 『Opast Tablet』for Neurologic Claudication in Patients With Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT01888536 Completed Yungjin Pharm. Co., Ltd. 2013-10-31
NCT01829997 Assessment of nanOss Bioactive 3D in the Posterolateral Spine https://ClinicalTrials.gov/show/NCT01829997 Completed Pioneer Surgical Technology, Inc. 2018-04-30
NCT01727752 A Randomized Controlled Trial Comparing Surgical Decompression With an Interlaminar Implant in Patients With Intermittent Neurogenic Claudication Caused by Lumbar Stenosis https://ClinicalTrials.gov/show/NCT01727752 Completed Paradigm Spine 2015-06-30
NCT01455805 Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT01455805 Active, not recruiting Spinal Simplicity LLC 2024-03-31
NCT00996073 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion https://ClinicalTrials.gov/show/NCT00996073 Completed Mesoblast, Ltd. 2012-07-31
NCT00549913 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) https://ClinicalTrials.gov/show/NCT00549913 Completed Mesoblast, Ltd. 2013-08-31
NCT04403360 Erector Spinae Plane Block After Lumbar Spinal Stenosis Surgery https://ClinicalTrials.gov/show/NCT04403360 Recruiting Clinique Saint Pierre Ottignies 2020-12-31
NCT04401735 Effects and Safety of Epidural PDRN vs. Placebo https://ClinicalTrials.gov/show/NCT04401735 Recruiting Seoul National University Hospital 2020-05-31
NCT04391855 Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery https://ClinicalTrials.gov/show/NCT04391855 Recruiting Aristotle University Of Thessaloniki 2020-11-30
NCT04330885 PRE Surgery reHABilitation for Spinal Stenosis https://ClinicalTrials.gov/show/NCT04330885 Recruiting Karolinska Institutet 2020-12-31
NCT04254757 Percutaneous Endoscopic Decompression for Lumbar Canal Stenosis https://ClinicalTrials.gov/show/NCT04254757 Recruiting Peking University Third Hospital 2021-12-31
NCT04204720 A Comparison of Intravascular Injection With Chiba Needle and Whitacre Needle https://ClinicalTrials.gov/show/NCT04204720 Completed Kyungpook National University Hospital 2019-12-15
NCT04193488 Mid-Transverse Process to Pleural (MTP) Block and Erector Spinal Plan (ESP) Block in Spinal Surgery https://ClinicalTrials.gov/show/NCT04193488 Completed Gulhane School of Medicine 2020-01-01
NCT04192591 A 5-year Superion® IDS Clinical Outcomes Post-Approval Evaluation (SCOPE) https://ClinicalTrials.gov/show/NCT04192591 Recruiting Boston Scientific Corporation 2024-01-31
NCT04189341 Modified-Thoracolumbar Interfascial Plane Block and Erector Spinae Plane Block Following Lumbar Instrumentation Surgery https://ClinicalTrials.gov/show/NCT04189341 Recruiting Medipol University 2020-08-30
NCT04094220 LLIF Plus Posterior Decompression for Severe Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT04094220 Recruiting Second Affiliated Hospital, School of Medicine, Zhejiang University 2021-08-01
NCT04087694 Microdecompression Versus Open Laminectomy and Posterior Stabilization for Multilevel Lumbar Spine Stenosis https://ClinicalTrials.gov/show/NCT04087694 Completed Hawler Medical University 2018-10-04
NCT04075539 Home-based Cycling for People With Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT04075539 Recruiting Assistance Publique - Hôpitaux de Paris 2022-10-31
NCT04062474 Epidural Intervention of Spinal Nerves With Tumor Necrosis Factor-Alpha Inhibitor https://ClinicalTrials.gov/show/NCT04062474 Completed Nanjing First Hospital, Nanjing Medical University 2016-12-15
NCT04042948 Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery https://ClinicalTrials.gov/show/NCT04042948 Recruiting Peking University Third Hospital 2020-05-28
NCT04007094 Single-Armed Use of ViviGen Cellular Bone Matrix in Patients Undergoing Posterolateral Lumbar Surgery https://ClinicalTrials.gov/show/NCT04007094 Recruiting Ohio State University 2021-12-31
NCT03968965 Evaluation of 3D Machine-vision Image Guided Surgery Spine Navigation https://ClinicalTrials.gov/show/NCT03968965 Recruiting 7D Surgical Inc. 2020-12-31
NCT03958526 Effectiveness of Transcranial Direct Current Stimulation in Chronic Pain Related to Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT03958526 Recruiting Istanbul University 2019-09-30
NCT03884283 Prospective, Multi-center Study to Assess Posterolateral Fusion Using FIBERGRAFT https://ClinicalTrials.gov/show/NCT03884283 Enrolling by invitation Prosidyan, Inc. 2021-02-28
NCT03883022 Vancomycin Powder Combined With Autogenous Bone Graft as a Prevention for Post-operative Infection for Spine Surgery https://ClinicalTrials.gov/show/NCT03883022 Recruiting Taipei Veterans General Hospital, Taiwan 2027-09-12
NCT03863067 Clinical Effectiveness, Security And Radiological Changes In Epiduroscopy For Lumbar Stenosis https://ClinicalTrials.gov/show/NCT03863067 Recruiting Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz 2019-10-15
NCT03801356 Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy https://ClinicalTrials.gov/show/NCT03801356 Recruiting The Cleveland Clinic 2020-08-23
NCT03784729 Efficacy of Acupuncture for Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT03784729 Recruiting Guang’anmen Hospital of China Academy of Chinese Medical Sciences 2020-06-30
NCT03754972 Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery https://ClinicalTrials.gov/show/NCT03754972 Recruiting Medical Metrics Diagnostics, Inc 2020-03-31
NCT03753945 Spine MRI in Patients With Deep Brain Stimulation (DBS) https://ClinicalTrials.gov/show/NCT03753945 Recruiting University Health Network, Toronto 2021-01-01
NCT03745040 Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion https://ClinicalTrials.gov/show/NCT03745040 Recruiting Allina Health System 2020-11-30
NCT03733626 Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease https://ClinicalTrials.gov/show/NCT03733626 Active, not recruiting William Beaumont Hospitals 2022-11-01
NCT03647501 Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages https://ClinicalTrials.gov/show/NCT03647501 Recruiting Ohio State University 2022-08-01
NCT03610737 The MOTION Study - Treatment of LSS With the MILD Procedure https://ClinicalTrials.gov/show/NCT03610737 Active, not recruiting Vertos Medical, Inc. 2020-07-30
NCT03570801 SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion https://ClinicalTrials.gov/show/NCT03570801 Recruiting Lahey Clinic 2021-10-31
NCT03560401 Is Postoperative Bracing Necessary After Spine Surgery for Degenerative Conditions https://ClinicalTrials.gov/show/NCT03560401 Completed Taipei Veterans General Hospital, Taiwan 2016-12-25
NCT03553186 Tranexamic Acid in Adult Spinal Deformity Surgery https://ClinicalTrials.gov/show/NCT03553186 Recruiting Hospital for Special Surgery, New York 2021-05-31
NCT03532945 A Follow-up Study to Evaluate the Efficacy and Safety of Novomax in Posterior Lumbar Interbody Fusion https://ClinicalTrials.gov/show/NCT03532945 Completed BioAlpha Inc. 2013-09-13
NCT03511053 Epidural Lavage Study https://ClinicalTrials.gov/show/NCT03511053 Active, not recruiting Dallas VA Medical Center 2020-07-18
NCT03495661 Decompression vs Physical Training for the Treatment of Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT03495661 Recruiting Uppsala University 2021-12-31
NCT01263678 Helping Patients With Spinal Stenosis Make a Treatment Decision: A Randomized Study Assessing The Benefits of Health Coaching https://ClinicalTrials.gov/show/NCT01263678 Completed Dartmouth-Hitchcock Medical Center 2013-05-31
NCT01238536 Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial) https://ClinicalTrials.gov/show/NCT01238536 Completed University of Washington 2013-08-31
NCT01131611 Cognitive-Behavioral Physical Therapy https://ClinicalTrials.gov/show/NCT01131611 Completed Vanderbilt University 2014-04-30
NCT01127100 Gabapentin Versus Transdermal Fentanyl Matrix for Chronic Neuropathic Pain https://ClinicalTrials.gov/show/NCT01127100 Completed Seoul National University Hospital 2011-11-30
NCT01097486 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy https://ClinicalTrials.gov/show/NCT01097486 Completed Mesoblast, Ltd. 2013-07-31
NCT01082159 MiDAS II (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study https://ClinicalTrials.gov/show/NCT01082159 Completed Vertos Medical, Inc. 2012-10-31
NCT01076244 Vertos Mild - Post Market Patient Outcomes https://ClinicalTrials.gov/show/NCT01076244 Completed The Center for Pain Relief, Inc. 2012-01-31
NCT01052324 The Effect Site Concentration of Remifentanil for Conscious Sedation During Awake Nasotracheal Fiberoptic Intubation https://ClinicalTrials.gov/show/NCT01052324 Completed Yonsei University 2010-11-30
NCT00995371 Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis https://ClinicalTrials.gov/show/NCT00995371 Completed Coastal Orthopedics & Sports Medicine 2012-06-30
NCT00956631 MiDAS I (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study https://ClinicalTrials.gov/show/NCT00956631 Completed Vertos Medical, Inc. 2012-04-30
NCT00939406 Clinical Trial to Evaluate Safety and Efficacy of Hyalospine® in Lumbar Laminectomy or Laminotomy https://ClinicalTrials.gov/show/NCT00939406 Completed AO Innovation Translation Center 2012-11-30
NCT00908375 Efficacy of Pregabalin in Patients With Radicular Pain https://ClinicalTrials.gov/show/NCT00908375 Completed Northwestern University 2012-09-30
NCT00905359 Neurogenic Intermittent Claudication Evaluation Study https://ClinicalTrials.gov/show/NCT00905359 Completed Medtronic Spinal and Biologics 2014-09-30
NCT00887744 Intermittent Neurogenic Claudication Treatment With APERIUS® https://ClinicalTrials.gov/show/NCT00887744 Completed Medtronic Spinal and Biologics 2009-05-31
NCT01452022 Performance of Inductigraft in Spinal Fusion https://ClinicalTrials.gov/show/NCT01452022 Completed Baxter Healthcare Corporation 2015-08-31
NCT00808665 Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion https://ClinicalTrials.gov/show/NCT00808665 Completed Vanderbilt University Medical Center 2012-12-31
NCT02644746 Efficacy and Safety of Acupuncture for Degenerative Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT02644746 Completed Guang’anmen Hospital of China Academy of Chinese Medical Sciences 2017-12-31
NCT02454400 Pre-surgery Physiotherapy for Patients With Specific Low Back Pain https://ClinicalTrials.gov/show/NCT02454400 Completed Linkoeping University 2017-10-31
NCT02416804 Postoperative Analgesia With Buprenorphine for Postoperative Pain Control and Quality of Life After Spinal Surgery https://ClinicalTrials.gov/show/NCT02416804 Completed Seoul National University Hospital 2016-07-31
NCT04039581 KT® in Patients With Cervical Spine Surgery https://ClinicalTrials.gov/show/NCT04039581 Active, not recruiting Marmara University 2020-07-31
NCT03969602 Cognitive Behavioral Therapy (CBT) After Lumbar Spinal Fusion in Patients With High Pain Catastrophizing https://ClinicalTrials.gov/show/NCT03969602 Recruiting Neurocenter of Southern Switzerland 2023-07-30
NCT00786981 Epidural Steroid Injection Versus Epidural Steroid Injection and Manual Physical Therapy and Exercise in the Management of Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT00786981 Completed Franklin Pierce University 2018-12-31
NCT00749073 The Vertos MILDâ„¢ Preliminary Patient Evaluation Study https://ClinicalTrials.gov/show/NCT00749073 Completed Vertos Medical, Inc. 2009-07-31
NCT00692276 Investigating Superionâ„¢ In Spinal Stenosis https://ClinicalTrials.gov/show/NCT00692276 Completed VertiFlex, Incorporated 2017-02-28
NCT00638443 Lumbar Stenosis Outcomes Research (LUSTOR) https://ClinicalTrials.gov/show/NCT00638443 Completed University of Rochester 2010-03-31
NCT00534235 Post-Approval Clinical Trial Comparing the Long Term Safety and Effectiveness Coflex vs. Fusion to Treat Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT00534235 Completed Paradigm Spine 2015-12-31
NCT00527527 Chiropractic Dosage for Lumbar Stenosis https://ClinicalTrials.gov/show/NCT00527527 Completed National University of Health Sciences 2010-01-31
NCT00493558 Spine Research With Roentgen Stereophotogrammetric Analysis https://ClinicalTrials.gov/show/NCT00493558 Completed Nova Scotia Health Authority 2012-06-30
NCT00405691 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis https://ClinicalTrials.gov/show/NCT00405691 Completed Impliant, Ltd. NA
NCT00405600 Spine Fusion Instrumented With BMP-2 vs Uninstrumented With Infuse BMP-2 Alone https://ClinicalTrials.gov/show/NCT00405600 Completed Nova Scotia Health Authority 2010-12-31
NCT00401518 A Pivotal Study of a Facet Replacement System to Treat Spinal Stenosis https://ClinicalTrials.gov/show/NCT00401518 Completed Globus Medical Inc 2017-08-31
NCT00370799 Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain https://ClinicalTrials.gov/show/NCT00370799 Completed Pain Management Center of Paducah 2009-12-31
NCT00320619 Epsilon-Aminocaproaic Acid to Reduce the Need for Blood Transfusions During and Following Spine Surgery https://ClinicalTrials.gov/show/NCT00320619 Completed National Heart, Lung, and Blood Institute (NHLBI) 2006-02-28
NCT00109213 Greenwich Lumbar Stenosis SLIP Study https://ClinicalTrials.gov/show/NCT00109213 Completed Greenwich Hospital 2009-09-30
NCT00022776 Surgical Versus Nonsurgical Treatment for Spinal Stenosis https://ClinicalTrials.gov/show/NCT00022776 Completed University of Pittsburgh 2007-12-31
NCT00000411 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis https://ClinicalTrials.gov/show/NCT00000411 Completed Dartmouth-Hitchcock Medical Center 2015-04-30
NCT00000409 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis https://ClinicalTrials.gov/show/NCT00000409 Completed Dartmouth-Hitchcock Medical Center 2015-04-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03325309 Barriers and Facilitators to Cycling for Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT03325309 Completed Assistance Publique - Hôpitaux de Paris 2016-12-21
NCT03321357 Retest-reliability and At-home-assessment Feasibility of the 5R-STS https://ClinicalTrials.gov/show/NCT03321357 Completed Bergman Clinics 2018-06-01
NCT03303300 The Five-repetition Sit-to-stand Test for Lower Back Pain or Radiculopathy https://ClinicalTrials.gov/show/NCT03303300 Completed Bergman Clinics 2017-12-01
NCT03194607 Quantitative Evaluation of Motor Function Before and After Surgery for Degenerative Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT03194607 Recruiting Centre Hospitalier Universitaire Dijon 2019-05-31
NCT03041896 Retrospective Evaluation of Performance of Coflex® Interlaminer Technology Versus Decompression With or Without Fusion https://ClinicalTrials.gov/show/NCT03041896 Completed Paradigm Spine 2017-12-31
NCT02931279 PASS OCT® Post-market Clinical Follow-up https://ClinicalTrials.gov/show/NCT02931279 Recruiting Medicrea International 2019-09-30
NCT02761928 Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients https://ClinicalTrials.gov/show/NCT02761928 Active, not recruiting The University of Texas Health Science Center, Houston 2025-12-31
NCT03072927 MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study https://ClinicalTrials.gov/show/NCT03072927 Recruiting Vertos Medical, Inc. 2022-12-31
NCT02529943 Changes in Motor Latency During Spinal Decompression: Relationship to Outcomes https://ClinicalTrials.gov/show/NCT02529943 Recruiting University of Saskatchewan 2021-10-31
NCT02257723 The Effect of Integrated CAM Treatment in Hospitalized Patients https://ClinicalTrials.gov/show/NCT02257723 Recruiting Jaseng Hospital of Korean Medicine 2030-12-31
NCT02215551 Predictors of Decompressive Laminectomy Outcomes https://ClinicalTrials.gov/show/NCT02215551 Active, not recruiting VA Office of Research and Development 2019-07-01
NCT02134821 Influence of Pain Sensitivity on Lumbar Surgery Outcomes https://ClinicalTrials.gov/show/NCT02134821 Completed Seoul National University Hospital 2014-04-30
NCT02064855 Evaluation of Fusion Rate Using K2M VESUVIUS® Demineralized Fibers With K2M EVEREST® Spinal System https://ClinicalTrials.gov/show/NCT02064855 Enrolling by invitation K2M, Inc. 2020-03-31
NCT02006901 Comparative Effectiveness of Microdecompression and Laminectomy for Central Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT02006901 Completed St. Olavs Hospital 2015-01-31
NCT01972256 A Study Comparing Fusion Rates of Two Lumbar Fusion Procedures https://ClinicalTrials.gov/show/NCT01972256 Completed Baxano Surgical, Inc. 2014-02-28
NCT01485289 Stabilimax Investigational Device Exemption (IDE) Clinical Investigation Patient Followup Study https://ClinicalTrials.gov/show/NCT01485289 Completed Rachiotek LLC 2012-11-30
NCT03898232 Fibergraft Interbody Fusion Retrospective https://ClinicalTrials.gov/show/NCT03898232 Enrolling by invitation Bone and Joint Clinic of Baton Rouge 2020-04-30
NCT04444739 Association Between Lumbar Muscle Atrophy, Sagittal Pelvic Alignment and Stenosis Grade in Patients With Degenerative Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT04444739 Recruiting University Hospital, Basel, Switzerland 2021-02-28
NCT04443738 Long Term Follow up of Spinal Stenosis Inpatients Treated With Korean Integrative Medicine Treatment. https://ClinicalTrials.gov/show/NCT04443738 Recruiting Jaseng Medical Foundation 2020-08-15
NCT04381663 CSS-Assessing the Course of Degenerative Cervical Spinal Stenosis Using Functional Outcomes https://ClinicalTrials.gov/show/NCT04381663 Enrolling by invitation University Hospital, Basel, Switzerland 2022-03-15
NCT04379765 Long-term Follow-up of Conservative and Surgical Treatment Results of Patients With Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT04379765 Recruiting Sisli Hamidiye Etfal Training and Research Hospital 2021-04-15
NCT04315090 Post-surgical Outcomes Measure Using the ERAS Protocol for Posterior Cervical Decompression and Fusion https://ClinicalTrials.gov/show/NCT04315090 Recruiting Mayo Clinic 2022-05-01
NCT04314453 Comparisons Therapeutic Effects of Different PELD Procedure on LSS. https://ClinicalTrials.gov/show/NCT04314453 Completed Second Affiliated Hospital of Wenzhou Medical University 2017-07-31
NCT04216992 Value of Three-dimensional Rotational Epidurography on Percutaneous Epidural Adhesiolysis https://ClinicalTrials.gov/show/NCT04216992 Completed Tri-Service General Hospital 2019-10-24
NCT04171544 Streamline Occipito-Cervico-Thoracic System Post-Market Clinical Follow-up https://ClinicalTrials.gov/show/NCT04171544 Enrolling by invitation RTI Surgical 2020-03-31
NCT04086784 3D-printed Porous Titanium Alloy Cages Versus PEEK Cages in Patients With Osteoporosis https://ClinicalTrials.gov/show/NCT04086784 Enrolling by invitation Peking University Third Hospital 2022-12-31
NCT04062942 The Six-Minute Walking Test (6WT) and Timed-Up-and-Go (TUG) Test as Measures of Objective Functional Impairment in Patients Undergoing Interlaminar or Transforaminal Epidural Steroid Injection for Lumbar Degenerative Disc Disease (DDD) https://ClinicalTrials.gov/show/NCT04062942 Recruiting Cantonal Hospital of St. Gallen 2020-07-15
NCT04058171 Validation of a Treadmill Walking Test to Discriminate Neurogenic Claudication From Vascular Claudication https://ClinicalTrials.gov/show/NCT04058171 Recruiting Université du Québec à Trois-Rivières 2020-12-30
NCT03977961 The Six-Minute Walking Test (6MWT) as a Measure of Functional Impairment in Lumbar Degenerate Disc Disease. https://ClinicalTrials.gov/show/NCT03977961 Recruiting Cantonal Hospital of St. Gallen 2020-05-01
NCT03956537 PMCF Neo Pedicle Screw and Cage Systems https://ClinicalTrials.gov/show/NCT03956537 Recruiting Neo Medical SA 2022-04-30
NCT03951935 Muscle Function and Pelvic Stability While Walking in Patients With Symptomatic Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT03951935 Recruiting University Hospital, Basel, Switzerland 2021-06-30
NCT03923920 Screening for Systemic Amyloidosis Via the Ligamentum Flavum https://ClinicalTrials.gov/show/NCT03923920 Recruiting The Cleveland Clinic 2021-04-01
NCT03910335 Diagnostic Screening Tool for Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT03910335 Completed University of Southern Denmark 2019-06-28
NCT03891745 Prone or Supine Extubation in Lomber Spinal Surgery https://ClinicalTrials.gov/show/NCT03891745 Recruiting Istanbul Medeniyet University 2019-07-01
NCT03863769 Chiropractic Distraction Spinal Manipulation- Lumbar Stenosis Study https://ClinicalTrials.gov/show/NCT03863769 Recruiting Parker University 2020-12-31
NCT03853356 Evidence For Fusion In Spine With Orthoss® https://ClinicalTrials.gov/show/NCT03853356 Recruiting Geistlich Pharma AG 2021-09-30
NCT03562936 The NORDSTEN Studies/The Observational Cohort Study https://ClinicalTrials.gov/show/NCT03562936 Recruiting Haukeland University Hospital 2018-10-01
NCT03532230 Cost Effectiveness of OMT for Chronic Low Back Pain https://ClinicalTrials.gov/show/NCT03532230 Completed Rowan University 2020-02-28
NCT01017692 Magnetic Resonance Imaging (MRI) Interpretations for Lumbar Spinal Stenosis (LSS) https://ClinicalTrials.gov/show/NCT01017692 Completed State University of New York - Upstate Medical University 2010-12-31
NCT01522846 Heparin Solution and INTEM/HEPTEM Analysis https://ClinicalTrials.gov/show/NCT01522846 Completed Seoul National University Bundang Hospital 2013-01-31
NCT02836730 Long-term Outcomes of Surgical and Nonsurgical Management of Sciatica Secondary to a Lumbar Disc Herniation or Spinal Stenosis https://ClinicalTrials.gov/show/NCT02836730 Completed Back and Rehabilitation Center, Copenhagen 2016-01-31
NCT03879447 Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis https://ClinicalTrials.gov/show/NCT03879447 Recruiting Jaseng Medical Foundation 2020-12-31
NCT00726284 Spine Patient Outcomes Registry for Biomet/EBI (Electro-Biology, Inc) https://ClinicalTrials.gov/show/NCT00726284 Completed Zimmer Biomet 2007-12-06
NCT00534092 Long-Term Outcomes for Lumbar Spinal Stenosis Patients Treated With X STOP® https://ClinicalTrials.gov/show/NCT00534092 Completed Medtronic Spinal and Biologics NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03398915 The European Robotic Spinal Instrumentation (EUROSPIN) Study https://ClinicalTrials.gov/show/NCT03398915 Recruiting Bergman Clinics 2021-09-01
NCT03064802 Burst Biologics Spinal Fusion Registry https://ClinicalTrials.gov/show/NCT03064802 Recruiting Smart-Surgical Inc. dba Burst Biologics 2020-06-30
NCT02897947 Outcome of Surgery for Lumbar Spinal Stenosis - a Comparison of Data From Three National Quality Registries https://ClinicalTrials.gov/show/NCT02897947 Completed St. Olavs Hospital 2013-12-31
NCT02457468 The Coflex®COMMUNITY Study: An Observational Study of Coflex® Interlaminar Technology https://ClinicalTrials.gov/show/NCT02457468 Completed Predicted, Reported and Observed Outcomes Foundation 2019-12-31
NCT04250753 Assessment of Gait Parameters and Their Impact on Postoperative Recovery in Patients With Lumbar Spinal Stenosis: a Feasibility Study https://ClinicalTrials.gov/show/NCT04250753 Recruiting Université du Québec à Trois-Rivières 2020-11-01
NCT04176562 Prospective SPINE Registry https://ClinicalTrials.gov/show/NCT04176562 Recruiting RTI Surgical 2025-03-31
NCT04087811 Postmarket Registry for Evaluation of the Superion® Spacer https://ClinicalTrials.gov/show/NCT04087811 Active, not recruiting Boston Scientific Corporation 2020-12-31
NCT04079894 Developing an Instrument for Measuring Walking Ability in Patients With Spinal Stenosis https://ClinicalTrials.gov/show/NCT04079894 Recruiting Spine Centre of Southern Denmark 2022-01-31
NCT03644407 Galeazzi Spine Surgery RegistryGaleazzi Spine Registry: Prospective Study for Clinical Monitoring https://ClinicalTrials.gov/show/NCT03644407 Recruiting Istituto Ortopedico Galeazzi 2025-01-01
NCT03434223 Prospective Follow-up of Elderly Patients Undergoing Instrumented Lumbar Arthrodesis Supplemented by the Implanet Jazz System(TM) https://ClinicalTrials.gov/show/NCT03434223 Recruiting Ohio State University 2021-12-01
NCT03548441 Comparative Effectiveness and Prognostic Factors of Surgical and Non-surgical Management of Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT03548441 Recruiting Spine Centre of Southern Denmark 2020-09-30
NCT04374669 Sarcopenia and Outcomes of Neuroplasty in Lumbar Spinal Stenosis https://ClinicalTrials.gov/show/NCT04374669 Recruiting Asan Medical Center 2021-05-31
NCT02411799 Instrumented Thoracic and Lumbar Arthrodesis Supplemented by the Implanet Jazz SystemTMd https://ClinicalTrials.gov/show/NCT02411799 Recruiting Ohio State University 2020-04-30